Our senses are the work of an ongoing evolutionary process and have equipped us with adequate tools for the world we live in. At the same time, the wish to modificate and alter the body refers to a long list of practices. From superficial tattoos and piercings to prosthesis, nutritional supplements that lead to greater physical performance over to drugs that can alter mental performance. Recent technological developments in biology, information technology and the ongoing miniaturisation of its components have opened the field for the next stage of enhancements. Technology has altered our lives radically and the human body seems to be the last border to be overcome. Some scientists see in this next step great promises to overcome natural human limitations, whereas others argue that by losing these limitations we lose the very core of what defines us as humans. No one can predict the future, but we are at the tipping point of a development that has started long ago. What has been, for the last decades, a field of science fiction has now become reality. Cyborgs, creatures transcending between nature and technology, already live among us. These developments bring a new role to the designer and the area of experience design, and therefore, challenge traditional approaches but also raise new ethical questions for designers and society. This paper addresses the question of how we might design meaningful artificial senses in the future, that are valuable for the user and accepted by society. A broad range of academic and professional literature, interviews with experts from different disciplines and user testings bring in different viewpoints to propose a set of recommendations when designing for body enhancing technologies. Hopefully, this research will provide a base for discussion about a development that started in the absence of public debate.